| S.N. | Exocrine glands | Endocrine glands |
| 1. | These glands have ducts. | These glands lack ducts. |
| 2. | Chemical substance secreted by exocrine glands is called enzyme. | They secrete a chemical substance called hormone. |
| 3. | They secrete and release enzymes through ducts in the target site. | They secrete and release their secretions directly into the blood stream. |
| 4. | They are located near the target site (site of action). | They are located far away from the target site. |
| 5. | They help in short term activity. | They help in long term activity related to different physiological activities of our body. |
| 6. | Examples: Salivary glands, Intestinal glands, Tear glands etc. | Examples: Pituitary gland, Thyroid glands, Adrenal glands etc. |