Differences between Active Transport and Passive Transport (Diffusion)

S.N. Active Transport Passive Transport (Diffusion)
1. The materials move through a bio-membrane against the concentration gradient or electrochemical gradient. The materials move across a bio-membrane along or down the concentration gradient or electrochemical gradient.
2.

 

Carrier molecules are needed for this process. It generally occurs without the help of carrier molecules but facilitated diffusion needs assistance from membrane proteins, such as channels and carriers.
3. Molecules move actively from the region of their lower concentration to the region of their higher concentration. Molecules move passively from the region of their higher concentration to the region of their lower concentration.
4. It uses energy of ATP or the movement of ions down a gradient across a membrane. No energy is used for this process.
5. It takes place in one direction only (unidirectional process). It takes place in both the directions.

 

6. It is affected by the oxygen supply, temperature and toxins (poisons). It is not affected by oxygen, temperature and toxins.
7. It is a rapid or fast process. It is a slow process.
8. It brings about selective uptake of materials like proteins, ions and complex sugars. It allows all transmissible molecules like water, oxygen,CO2, small sugars etc. to pass across membranes.
9. It is stopped by metabolic inhibitors. It is not influenced by metabolic inhibitors.
10. Leads to accumulation of materials in the cells. It doesn’t accumulate the materials in the cells.
11. It is a vital process, i.e. allows the transportation of nutrients and wastes against the concentration gradient. It is one of the normal physical processes which maintains a dynamic equilibrium of water, gases, nutrients and wastes in and out of the cell.
12. No equilibrium of molecules is established. No net movement of molecules is observed after the establishment of equilibrium on either side of the membrane.

Differences between Active Transport and Passive Transport (Diffusion)